SCHEMBL4451596

SCHEMBL4451596

Cc1ccccc1O[PH](=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
RXRG P48443 1/20 0.39
NOTUM Q6P988 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ACHE P22303 1/20 0.38
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30716857 0.84 CA1 (0.35) TSHRKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL545054 0.83 MAPT (0.47) MEN1KMT2ANPC1RAB9ATDP1
SCHEMBL3281430 0.82 TSHR (0.43) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28811500 0.80 MAPT (0.33) TSHRMEN1KMT2ATDP1ATM
SCHEMBL14007529 0.80 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL2895269 0.77 TSHR (0.39) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL2822983 0.77 L3MBTL1 (0.48) TSHRMEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL18037101 0.76 CA2 (0.48) TSHRKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL31451612 0.76 CA2 (0.48) TSHRKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL10589808 0.76 ALDH1A1 (0.40) TSHRMEN1KMT2ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4092316-A Synthesis of C-alkyl-triethylenediamines TEXACO DEVELOPMENT CORPORATION (US) 1978-05-30 US claimed
US-4036881-A FROM ALKYLENEAMINE AND ALKANOLAMINE TEXACO DEVELOPMENT CORPORATION (US) 1977-07-19 US claimed
US-10479809-B2 Method for producing alkenyl phosphorus compound MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-11-19 US disclosed
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-08-29 US disclosed
EP-3348561-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND Maruzen Petrochemical Co., Ltd. (JP) 2018-07-18 EP disclosed
US-9920083-B2 Image recording paper medium and image recording method FUJIFILM CORPORATION (JP) 2018-03-20 US disclosed
CN-107107049-A Selective hydrogenation catalyst and its preparation and application 切弗朗菲利浦化学公司 2017-08-29 CN disclosed
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2016-09-01 US disclosed
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed
EP-0078000-B1 A PROCESS FOR PREPARING ALLYLAMINES FROM ALLYL ALCOHOL AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-05-28 EP disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 US disclosed
US-4117227-A PRODUCTION OF N-(SUBSTITUTED) MORPHOLINE TEXACO DEVELOPMENT CORP. (US) 1978-09-26 US disclosed
US-4095022-A PHOSPHORUS COMPOUNDS, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1978-06-13 US disclosed
US-4092316-A Synthesis of C-alkyl-triethylenediamines TEXACO DEVELOPMENT CORPORATION (US) 1978-05-30 US disclosed
US-4066649-A METHOD OF PRODUCING N,N'-(DIMETHYL) PIPERAZINE COMPOUNDS TEXACO DEVELOPMENT CORPORATION (US) 1978-01-03 US disclosed
US-4049657-A FROM A PIPERAZINE AND A PRIMARY OR SECONDARY AMINOALKANOL, PHOSPHORUS-CONTAINING CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1977-09-20 US disclosed
US-4044053-A Preparation of polyalkylene polyamines TEXACO DEVELOPMENT CORPORATION (US) 1977-08-23 US disclosed
US-4036881-A FROM ALKYLENEAMINE AND ALKANOLAMINE TEXACO DEVELOPMENT CORPORATION (US) 1977-07-19 US disclosed
US-4026935-A FROM N-(HYDROXYALKYL)-MORPHOLINE COMPOUND, SILICA-ALUMINA CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479809-B2 Method for producing alkenyl phosphorus compound ORC3, OR10J3, ORAI3 TSHR 1438/4885MEN1 2229/4885KMT2A 3129/4885
US-20160250866-A1 IMAGE RECORDING PAPER MEDIUM AND IMAGE RECORDING METHOD PHOSPHO1, ITPR2, PPIP5K2 TSHR 3882/4885MEN1 919/4885KMT2A 3383/4885
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND ORC3, OR10J3, ALK TSHR 1162/4885MEN1 2433/4885KMT2A 2957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.