Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 5/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274280 | 0.86 | AKR1C2 (0.47) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| Hydrochloric Acid SCHEMBL9194113 | 0.84 | AKR1C2 (0.46) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL7412553 | 0.79 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL4466616 | 0.78 | AKR1C2 (0.57) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL30023765 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL13064872 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28883530 | 0.78 | AKR1C2 (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL29186005 | 0.77 | ALDH1A1 (0.46) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL10917707 | 0.77 | CYP3A4 (0.48) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL23823369 | 0.75 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114854803-A | Method for biodegradation of 3, 6-dichlorocarbazole by fusarium | 山东农业大学 | 2022-08-05 | — | — | CN | disclosed |