Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 9/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 9/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691741 | 0.86 | AKR1C2 (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL28030639 | 0.84 | DPP4 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL5961110 | 0.83 | AKR1C2 (0.59) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL25925492 | 0.80 | TPMT (0.51) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL29608104 | 0.79 | GAA (0.47) | KDM4EMEN1KMT2AHPGDMAPT | |
| SCHEMBL23823337 | 0.79 | DHODH (0.41) | AKR1C2AKR1C1AKR1C4AKR1C3TTR | |
| SCHEMBL18394239 | 0.79 | GAA (0.47) | KDM4EMEN1KMT2AHPGDMAPT | |
| SCHEMBL39512 | 0.78 | CSNK2A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL3761832 | 0.78 | HMGB1 (0.52) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL4466616 | 0.78 | AKR1C2 (0.57) | AKR1C2AKR1C1AKR1C4AKR1C3TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954787-A | Modulators of methyl-modified enzymes, compositions and uses thereof | 星座制药公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-111989325-B | Modulators of methyl-modified enzymes, compositions and uses thereof | 星座制药公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2021180235-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | 四川海思科制药有限公司 | 2021-09-16 | — | — | WO | disclosed |