SCHEMBL28811776

SCHEMBL28811776

[CH2]C(C)(C)Cc1ccncc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.44
LOXL2 Q9Y4K0 2/20 0.42
CYP3A4 P08684 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP2D6 P10635 2/20 0.41
HSD17B10 Q99714 1/20 0.41
RAB9A P51151 1/20 0.38
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
KIF11 P52732 1/20 0.37
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
CHRM1 P11229 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73475 0.80 ESR1 (0.52) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL6205695 0.76 SLC6A2 (0.60) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL8843066 0.76 CYP3A4 (0.46) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL3236715 0.76 FDPS (0.53) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL27574461 0.76 FDPS (0.40) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL2313943 0.75 SLC6A2 (0.58) FDPSCYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL8362815 0.74 BRS3 (0.45) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL13715390 0.74 LOXL2 (0.43) FDPSLOXL2CYP3A4CYP1A2CYP2C9
SCHEMBL2376699 0.74 CYP1A2 (0.51) FDPSCYP3A4CYP1A2CYP2C9CYP2C19
Ammonia Solution, Strong SCHEMBL29011215 0.73 SLC6A2 (0.56) FDPSCYP3A4CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103787959-A N-2,2-dimethyl-3-arylpropylcaprylamide compound, its preparation method and its use in pharmacy UNIV CHINA PHARMA 2014-05-14 CN disclosed