Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721781 | 0.86 | CHRM2 (0.59) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19403863 | 0.85 | SLC9A1 (0.50) | SLC9A1MAPTL3MBTL1HRH3SLC6A3 | |
| SCHEMBL14708134 | 0.85 | SLC9A1 (0.50) | SLC9A1MAPTL3MBTL1HRH3SLC6A3 | |
| SCHEMBL4140532 | 0.85 | SLC9A1 (0.50) | SLC9A1MAPTL3MBTL1HRH3SLC6A3 | |
| SCHEMBL20525002 | 0.85 | CHRM2 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL15241291 | 0.81 | RAB9A (0.54) | MAPTL3MBTL1RAB9A | |
| SCHEMBL6691356 | 0.80 | PDE4A (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6698171 | 0.80 | PDE4A (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6691364 | 0.80 | PDE4A (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6698173 | 0.80 | PDE4A (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103781763-A | Amine derivatives as potassium channel blockers | BIONOMICS LTD | 2014-05-07 | — | — | CN | disclosed |