SCHEMBL28811862

SCHEMBL28811862

CC(C(=O)O)(c1ccccc1)c1cccnc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
LMNA P02545 1/20 0.54
CYP11B1 P15538 1/20 0.54
CYP11B2 P19099 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KCNA5 P22460 3/20 0.47
KDM4E B2RXH2 1/20 0.46
CYP19A1 P11511 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19031874 0.90 CYP3A4 (0.51) CYP1A2CYP3A4LMNACYP11B1CYP11B2
SCHEMBL26133831 0.86 LMNA (0.51) CYP1A2CYP3A4LMNACYP11B1CYP11B2
SCHEMBL19031888 0.84 HDAC3 (0.47) CYP1A2CYP3A4LMNACYP11B1CYP11B2
Hydrochloric Acid SCHEMBL27886095 0.82 HDAC3 (0.57) CYP1A2CYP3A4KDM4EHDAC3HDAC4
SCHEMBL73063 0.82 HDAC3 (0.61) CYP1A2CYP3A4TDP1KDM4EHDAC3
SCHEMBL4702232 0.81 LMNA (0.67) CYP1A2CYP3A4LMNACYP11B1CYP11B2
SCHEMBL10772486 0.81 LMNA (0.57) CYP1A2CYP3A4LMNACYP11B1CYP11B2
SCHEMBL19625585 0.81 LMNA (0.57) CYP1A2CYP3A4LMNACYP11B1CYP11B2
Hydrochloric Acid SCHEMBL3674757 0.80 HDAC3 (0.59) CYP1A2CYP3A4TDP1KDM4EHDAC3
Bromomethane SCHEMBL209562 0.80 HDAC3 (0.59) CYP1A2CYP3A4TDP1KDM4EHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103906743-A Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi PIRAMAL IMAGING SA 2014-07-02 CN claimed
CN-103906743-A Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi PIRAMAL IMAGING SA 2014-07-02 CN disclosed