Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119223 | 0.85 | EPHX2 (0.60) | EPHX2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL29401765 | 0.85 | EPHX2 (0.60) | EPHX2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL29913938 | 0.85 | EPHX2 (0.60) | EPHX2KDM4EKMT2AL3MBTL1 | |
| SCHEMBL15186931 | 0.84 | RAB9A (0.60) | EPHX2ALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL31126834 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL2860044 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10LMNAKMT2A | |
| SCHEMBL29342668 | 0.82 | EPHX2 (0.57) | EPHX2KMT2ATP53 | |
| SCHEMBL9588677 | 0.82 | EPHX2 (0.56) | EPHX2ALDH1A1KMT2AHTTL3MBTL1 | |
| SCHEMBL569859 | 0.82 | EPHX2 (0.54) | EPHX2KDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL8088703 | 0.81 | EPHX2 (0.56) | EPHX2ALDH1A1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736131-A | Synthetic method of bromfenac sodium | 郑州灏瑞医药科技有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114736131-A | Synthetic method of bromfenac sodium | 郑州灏瑞医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736131-A | Synthetic method of bromfenac sodium | 郑州灏瑞医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |