SCHEMBL29401765

SCHEMBL29401765

O=C(Nc1ccccc1C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.60
KMT2A Q03164 4/20 0.56
FABP7 O15540 2/20 0.46
FABP5 Q01469 2/20 0.46
CHRM3 P20309 3/20 0.45
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.45
CASP3 P42574 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29913938 1.00 EPHX2 (0.60) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL119223 1.00 EPHX2 (0.60) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL3209124 0.92 EPHX2 (0.55) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL29342668 0.90 EPHX2 (0.57) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL569859 0.89 EPHX2 (0.54) EPHX2KMT2ACASP3NPC1RAB9A
SCHEMBL8088703 0.88 EPHX2 (0.56) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL15186922 0.87 EPHX2 (0.61) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL3203815 0.87 EPHX2 (0.65) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL6346117 0.87 EPHX2 (0.52) EPHX2KMT2AFABP7FABP5CHRM3
SCHEMBL1157612 0.86 EPHX2 (0.57) EPHX2KMT2AFABP7FABP5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400614-A1 CLEAVABLE PEPTIDES AND METHODS OF USE THEREOF BRIGHT PEAK THERAPEUTICS AG (CH) 2024-12-05 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
WO-2024150172-A1 CLEAVABLE PEPTIDES AND METHODS OF USE THEREOF BRIGHT PEAK THERAPEUTICS AG (CH) 2024-07-18 WO disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400614-A1 CLEAVABLE PEPTIDES AND METHODS OF USE THEREOF DNPEP, TMPRSS15, CPB1 EPHX2 2908/4885KMT2A 3925/4885FABP7 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.