Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488329 | 0.83 | LOXL2 (0.50) | LOXL2CYP2A6MTNR1AMTNR1BHRH3 | |
| SCHEMBL4384511 | 0.77 | LOXL2 (0.63) | LOXL2OPRK1MTNR1AMTNR1BHRH3 | |
| SCHEMBL28886053 | 0.77 | LOXL2 (0.58) | LOXL2OPRK1MTNR1AMTNR1BHRH3 | |
| SCHEMBL2111019 | 0.77 | LOXL2 (0.58) | LOXL2OPRK1MTNR1AMTNR1BHRH3 | |
| SCHEMBL108898 | 0.77 | LOXL2 (0.58) | LOXL2CYP2A6OPRK1MTNR1AMTNR1B | |
| SCHEMBL29796415 | 0.77 | LOXL2 (0.58) | LOXL2CYP2A6OPRK1MTNR1AMTNR1B | |
| SCHEMBL15662691 | 0.77 | LOXL2 (0.58) | LOXL2OPRK1MTNR1AMTNR1BHRH3 | |
| SCHEMBL6715530 | 0.76 | LOXL2 (0.53) | LOXL2CYP2A6OPRK1MTNR1AMTNR1B | |
| SCHEMBL4280580 | 0.75 | LOXL2 (0.56) | LOXL2OPRK1MTNR1AMTNR1BHRH3 | |
| SCHEMBL27487578 | 0.74 | LOXL2 (0.47) | LOXL2CYP2A6MTNR1AMTNR1BHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874406-A | Indolyl sulfonamide compound and preparation method and application thereof | 山东大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114907344-B | Beta-carboline-1-propionic acid and indole derivatives, and preparation method and application thereof | 山东大学 | 2023-06-30 | — | — | CN | claimed |
| CN-114907344-A | Beta-carboline-1-propionic acid and indole derivatives, and preparation method and application thereof | 山东大学 | 2022-08-16 | — | — | CN | claimed |
| CN-116874406-A | Indolyl sulfonamide compound and preparation method and application thereof | 山东大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-114907344-B | Beta-carboline-1-propionic acid and indole derivatives, and preparation method and application thereof | 山东大学 | 2023-06-30 | — | — | CN | disclosed |