Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745986 | 0.85 | LOXL2 (0.51) | LOXL2DPP4CYP2A6MTNR1AMTNR1B | |
| SCHEMBL27934322 | 0.84 | LOXL2 (0.46) | LOXL2DPP4CYP2A6MTNR1AMTNR1B | |
| SCHEMBL27992847 | 0.84 | LOXL2 (0.46) | LOXL2DPP4CYP2A6MTNR1AMTNR1B | |
| SCHEMBL27807522 | 0.84 | LOXL2 (0.46) | LOXL2DPP4CYP2A6MTNR1AMTNR1B | |
| SCHEMBL27738751 | 0.81 | FLT3 (0.39) | LOXL2HRH4 | |
| SCHEMBL27570412 | 0.81 | ALOX15 (0.46) | LOXL2HRH4 | |
| SCHEMBL27489310 | 0.81 | KDM4E (0.40) | LOXL2DPP4KDM4ELMNA | |
| SCHEMBL28781244 | 0.81 | LOXL2 (0.41) | LOXL2DPP4CYP2A6MTNR1AMTNR1B | |
| SCHEMBL9027554 | 0.79 | LOXL2 (0.58) | LOXL2DPP4MTNR1AMTNR1BCASR | |
| SCHEMBL27657205 | 0.77 | LOXL2 (0.43) | LOXL2DPP4CYP2A6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101547914-A | Indoles compound | HOFFMANN LA ROCHE (CH) | 2009-09-30 | — | — | CN | disclosed |
| CN-101547923-A | Spiro-piperidine derivatives as VIA receptor antagonists | HOFFMANN LA ROCHE (CH) | 2009-09-30 | — | — | CN | disclosed |
| CN-101541797-A | Spiro-piperidine derivatives | HOFFMANN LA ROCHE (CH) | 2009-09-23 | — | — | CN | disclosed |
| CN-101321726-A | Novel fused pyrrole derivative | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-12-10 | — | — | CN | disclosed |
| CN-1197860-C | FAB I inhibitors | SMITHKLINE BEECHAM CORP (CA) | 2005-04-20 | — | — | CN | disclosed |
| CN-1378542-A | Antigen binding fragment I inhibitors | SMITHKLINE BEECHAM CORP (US) | 2002-11-06 | — | — | CN | disclosed |