Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690106 | 1.00 | KMT2A (0.41) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL29731103 | 1.00 | KMT2A (0.41) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL29730888 | 0.95 | KMT2A (0.39) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL28812491 | 0.95 | KMT2A (0.39) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL21690547 | 0.95 | KMT2A (0.39) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL21643537 | 0.92 | MTNR1A (0.47) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL21689953 | 0.92 | MTNR1A (0.47) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL29731075 | 0.92 | MTNR1A (0.47) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL24846026 | 0.88 | L3MBTL1 (0.38) | KMT2AMEN1GAALMNAMAPT | |
| SCHEMBL21643315 | 0.88 | L3MBTL1 (0.38) | KMT2AMEN1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746103-A | Rapafucin derivative compounds and methods of use thereof | 约翰霍普金斯大学 | 2022-07-12 | — | — | CN | disclosed |