Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | NAMPT | P43490 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612365 | 0.90 | NAMPT (0.60) | CYP11B1CYP11B2LMNANAMPTALDH1A1 | |
| SCHEMBL4315835 | 0.88 | CYP11B1 (0.65) | CYP11B1CYP11B2LMNANAMPTHDAC1 | |
| SCHEMBL28162546 | 0.88 | CYP11B1 (0.54) | CYP11B1CYP11B2LMNANAMPTHDAC1 | |
| SCHEMBL20379257 | 0.88 | CYP11B1 (0.54) | CYP11B1CYP11B2LMNANAMPTHDAC1 | |
| SCHEMBL4317112 | 0.84 | POLB (0.58) | CYP11B1CYP11B2LMNANAMPTALDH1A1 | |
| SCHEMBL2095827 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2LMNANAMPTHDAC1 | |
| SCHEMBL10612370 | 0.81 | LMNA (0.51) | CYP11B1CYP11B2LMNANAMPTALDH1A1 | |
| SCHEMBL3492794 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2LMNAHDAC1HDAC2 | |
| SCHEMBL6973608 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2LMNAHDAC1HDAC2 | |
| SCHEMBL2226354 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2LMNANAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104109155-A | Novel compounds | TANABE SEIYAKU CO | 2014-10-22 | — | — | CN | disclosed |
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |