Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762765 | 0.83 | SMN1; SMN2 (0.49) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL2095827 | 0.82 | CYP11B1 (0.54) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL21753345 | 0.81 | CYP11B1 (0.47) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27955951 | 0.81 | CYP11B1 (0.37) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL2226354 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3492794 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28812866 | 0.81 | CYP11B1 (0.65) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1895825 | 0.81 | CYP11B1 (0.56) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL153089 | 0.81 | CYP11B1 (0.56) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL18667423 | 0.80 | CYP11B1 (0.49) | CYP11B1CYP11B2ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270737-A1 | SMALL MOLECULAR INHIBITORS OF STING SIGNALING COMPOSITIONS AND METHODS OF USE | STINGINN INC. (US) | 2024-08-15 | — | — | US | disclosed |
| CN-113968799-B | Malononitrile compound and application thereof | 沈阳化工大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-113968799-A | Malononitrile compound and application thereof | 沈阳化工大学 | 2022-01-25 | — | — | CN | disclosed |
| US-20200040025-A1 | URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | TUFTS UNIVERSITY | 2020-02-06 | — | — | US | disclosed |
| WO-2018058148-A1 | URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | TUFTS UNIVERSITY (US) | 2018-03-29 | — | — | WO | disclosed |
| US-6548667-B2 | For prevention and treatment of diseases caused by overexpression and overactivation of matrix metalloproteinase | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-04-15 | — | — | US | disclosed |
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| US-20020169314-A1 | Sulfonamide derivative as a matrix metalloproteinase inhibitor | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2002-11-14 | — | — | US | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |
| EP-0665222-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| CN-1026981-C | Process for the preparation of guanidine derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-14 | — | — | CN | disclosed |
| CN-1077843-A | GUANIDINE DERIVATIVES, THEIR PRODUCTION AND INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| EP-0222576-B1 | HETEROCYCLIC OXOPHTHALAZINYL ACETIC ACIDS | PFIZER INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-1009831-B | PROCESS FOR PREPARING HETEROCYCLE-OXO-2,3-DIAZANAPHTHYL-ACETIC ACID | PFIZER (US) | 1990-10-03 | — | — | CN | disclosed |
| CN-1045261-A | Guanidine derivatives, their production and pesticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-09-12 | — | — | CN | disclosed |
| EP-0376279-A2 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |
| CN-86108308-A | Heterocycle oxo-2 guanidine-acetic acid | — | 1987-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270737-A1 | SMALL MOLECULAR INHIBITORS OF STING SIGNALING COMPOSITIONS AND METHODS OF USE | STING1, IRF3, MAVS | CYP11B1 3773/4885CYP11B2 3978/4885ALDH1A1 4812/4885 |
| US-20020169314-A1 | Sulfonamide derivative as a matrix metalloproteinase inhibitor | MMP9, MMP3, MMP14 | CYP11B1 1497/4885CYP11B2 1597/4885ALDH1A1 311/4885 |
| US-20200040025-A1 | URIDINE NUCLEOSIDE DERIVATIVES, COMPOSITIONS AND METHODS OF USE | P2RY6, UPP1, UMPS | CYP11B1 3232/4885CYP11B2 3228/4885ALDH1A1 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.