SCHEMBL28813

SCHEMBL28813

CCCCCC(N)OP(=O)(OC(N)CCCCC)OC(N)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 2/20 0.50
S1PR2 O95136 5/20 0.48
S1PR1 P21453 5/20 0.48
S1PR3 Q99500 5/20 0.48
S1PR4 O95977 4/20 0.48
SMPD1 P17405 3/20 0.47
OPRM1 P35372 1/20 0.44
FDPS P14324 4/20 0.43
TP53 P04637 1/20 0.41
GRIK1 P39086 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
GRIK2 Q13002 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13735694 0.98 LAP3 (0.52) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL11333556 0.93 CYP3A4 (0.44) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL15772432 0.91 S1PR2 (0.46) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL29232553 0.85 CYP3A4 (0.53) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL10421805 0.85 CYP3A4 (0.53) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL3644479 0.85 LAP3 (0.48) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL28814 0.83 SMPD1 (0.63) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL6580829 0.82 S1PR2 (0.49) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL8377533 0.82 SMPD1 (0.67) LAP3S1PR2S1PR1S1PR3S1PR4
SCHEMBL2745581 0.82 SMPD1 (0.67) LAP3S1PR2S1PR1S1PR3S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2932 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043082-A2 COMPOSITIONS AND METHODS TO IMPROVE RNA PROPERTIES USING BASE, PHOSPHODIESTER LINKAGE, SUGAR BACKBONE, AND CAP MODIFICATIONS THE BROAD INSTITUTE, INC. (US) 2025-02-27 WO claimed
US-9328347-B2 siRNA useful in the treatment of flavivirus infection OREGON HEALTH & SCIENCE UNIVERSITY (US) 2016-05-03 US claimed
US-8846631-B2 MicroRNA compositions and methods Regulus Therapeutics Inc. (US) 2014-09-30 US claimed
US-20140287023-A1 5'-TRIPHOSPHATE OLIGORIBONUCLEOTIDES UNIV MCGILL (CA) 2014-09-25 US claimed
US-20140248336-A1 SIRNA USEFUL IN THE TREATMENT OF FLAVIVIRUS INFECTION OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-09-04 US claimed
WO-2014124433-A1 5'-TRIPHOSPHATE OLIGORIBONUCLEOTIDES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2014-08-14 WO claimed
WO-2013012835-A2 SIRNA USEFUL IN THE TREATMENT OF FLAVIVIRUS INFECTION OREGON HEALTH & SCIENCE UNIVERSITY (US) 2013-01-24 WO claimed
JP-2003525017-A 2003-08-26 JP claimed
JP-2002526072-A 2002-08-20 JP claimed
JP-2002520051-A 2002-07-09 JP claimed
EP-1115859-A2 HAIRPIN HYBRIDIZER MOLECULES FOR MODULATION OF GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2001-07-18 EP claimed
EP-1108724-A2 Synthesis of methoxy nucleosides and enzymatic nucleic acid molecules RIBOZYME PHARMACEUTICALS, INC. (US) 2001-06-20 EP claimed
EP-1098969-A2 USE OF NUCLEIC ACID MOLECULES AS ANTIVIRAL AGENTS RIBOZYME PHARMACEUTICALS, INC. (US) 2001-05-16 EP claimed
EP-1071753-A2 NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2001-01-31 EP claimed
WO-2000017346-A2 HAIRPIN HYBRIDIZER MOLECULES FOR MODULATION OF GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2000-03-30 WO claimed
WO-2000004141-A2 USE OF NUCLEIC ACID MOLECULES AS ANTIVIRAL AGENTS RIBOZYME PHARMACEUTICALS, INC. (US) 2000-01-27 WO claimed
US-5998203-A PARTICULARLY USEFUL FOR ENZYMATIC CLEAVAGE OF RNA OR SINGLE-STRANDED DNA. RIBOZYME PHARMACEUTICALS, INC. (US) 1999-12-07 US claimed
WO-1999054459-A2 NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 1999-10-28 WO claimed
EP-0886641-A2 SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES RIBOZYME PHARMACEUTICALS, INC. (US) 1998-12-30 EP claimed
WO-1997026270-A2 SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES RIBOZYME PHARMACEUTICALS, INC. (US) 1997-07-24 WO claimed