Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874208 | 0.91 | KDM4E (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2877206 | 0.91 | KDM4E (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2874240 | 0.91 | KDM4E (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2879111 | 0.90 | IKBKB (0.37) | MAPTKDM4ERAB9ANPC1POLB | |
| SCHEMBL2878697 | 0.89 | HDAC6 (0.31) | CHEK1 | |
| SCHEMBL2874941 | 0.89 | NPC1 (0.36) | HSD17B1HSD17B2MAPTKDM4ERAB9A | |
| SCHEMBL2876896 | 0.89 | NR1I2 (0.31) | — | |
| SCHEMBL2879246 | 0.88 | HDAC1 (0.32) | HSD17B1HSD17B2KDM4EMAP3K8CHEK1 | |
| SCHEMBL2876853 | 0.87 | PTPN1 (0.39) | MAPTKDM4ERAB9ANPC1CASP3 | |
| SCHEMBL2879449 | 0.86 | KDM4E (0.36) | KDM4EKMT2AMEN1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |