Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874240 | 0.90 | KDM4E (0.38) | — | |
| SCHEMBL2877206 | 0.90 | KDM4E (0.38) | — | |
| SCHEMBL2874208 | 0.90 | KDM4E (0.38) | — | |
| SCHEMBL2879111 | 0.89 | IKBKB (0.37) | — | |
| SCHEMBL2881302 | 0.89 | HSD17B1 (0.34) | CHEK1 | |
| SCHEMBL2874941 | 0.89 | NPC1 (0.36) | HDAC6CHEK1 | |
| SCHEMBL2878694 | 0.87 | NR1I2 (0.38) | HDAC6MMP12 | |
| SCHEMBL2879246 | 0.87 | HDAC1 (0.32) | HDAC6STK17BCHEK1 | |
| SCHEMBL2876896 | 0.86 | NR1I2 (0.31) | — | |
| SCHEMBL2879449 | 0.85 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |