Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972306 | 0.81 | PTGS1 (0.50) | AKR1B1POLBNSD2GRK2CASP6 | |
| SCHEMBL28195327 | 0.81 | METTL3 (0.42) | POLBMETTL3METTL14KDM4EALDH1A1 | |
| SCHEMBL28042211 | 0.81 | AKR1B1 (0.45) | AKR1B1POLBNSD2GRK2CASP6 | |
| SCHEMBL27972289 | 0.79 | ABCC4 (0.56) | AKR1B1LMNAPTGS1GAATSHR | |
| SCHEMBL2760780 | 0.78 | NPC1 (0.43) | POLBMETTL3METTL14TSHRKDM4E | |
| SCHEMBL17372780 | 0.75 | SMN1; SMN2 (0.41) | POLBMETTL3METTL14LMNAKDM4E | |
| SCHEMBL2940146 | 0.74 | MAPT (0.43) | POLBMETTL3METTL14LMNAGAA | |
| SCHEMBL2691734 | 0.74 | NPC1 (0.43) | POLBMETTL3METTL14KDM4EALDH1A1 | |
| SCHEMBL1759104 | 0.73 | CHRNA7 (0.49) | POLBPTGS1TSHRPTGS2KDM4E | |
| SCHEMBL27620623 | 0.72 | TSHR (0.52) | POLBMETTL3METTL14TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923105-A | 2-indolizine formylamine compound as well as preparation method and application thereof | UNIV BEIJING | 2014-07-16 | — | — | CN | disclosed |