Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 14/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25063332 | 0.81 | GAA (0.44) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL11455539 | 0.78 | GLS (0.42) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL18633046 | 0.77 | GLS (0.44) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL15248092 | 0.76 | GLS (0.43) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL10042081 | 0.76 | GLS (0.43) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL8056438 | 0.75 | GLS (0.42) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL15945413 | 0.75 | GLS (0.42) | GLSKDM4ELMNAHTTKDM4A | |
| SCHEMBL28060180 | 0.75 | KDM4E (0.38) | GLSKDM4ELMNAL3MBTL1CA12 | |
| SCHEMBL18605522 | 0.73 | SMN1; SMN2 (0.50) | GLSHTT | |
| SCHEMBL27903373 | 0.72 | KDM4E (0.42) | KDM4ELMNAHTTKDM4AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917528-A | Pyrimidine PDE10 inhibitors | MERCK SHARP & DOHME | 2014-07-09 | — | — | CN | disclosed |