Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036878 | 0.87 | POLB (0.32) | POLBCA12CA1CA2CA9 | |
| SCHEMBL30008276 | 0.79 | POLB (0.40) | POLBCA12CA1CA2CA9 | |
| SCHEMBL262483 | 0.73 | POLB (0.43) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11801523 | 0.73 | POLB (0.43) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL14561060 | 0.70 | POLB (0.41) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL21828164 | 0.70 | CYP3A4 (0.41) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL194844 | 0.70 | POLB (0.42) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7617677 | 0.68 | GAA (0.41) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2087057 | 0.67 | SLC1A3 (0.37) | — | |
| SCHEMBL1903133 | 0.67 | CA2 (0.42) | POLBCA1CA2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587417-A1 | PHARMACEUTICAL FORMS OF A CD73 INHIBITOR | Oric Pharmaceuticals, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059609-A1 | PHARMACEUTICAL FORMS OF A CD73 INHIBITOR | ORIC PHARMACEUTICALS, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-114929721-A | CD73 inhibitor | 欧瑞克制药公司 | 2022-08-19 | — | — | CN | disclosed |