SCHEMBL27240703

SCHEMBL27240703

N=C(N)NCC(=O)Oc1ccccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
JAK2 O60674 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
CA1 P00915 3/20 0.37
CA12 O43570 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
PLG P00747 1/20 0.36
PLAU P00749 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27506281 0.84 L3MBTL1 (0.50) ATMPOLBKMT2ALMNAMAPT
SCHEMBL27384745 0.83 L3MBTL1 (0.39) GAAKMT2ALMNAMAPTKDM4E
SCHEMBL27758859 0.83 ALDH1A1 (0.46) GAAATMKMT2AMAPTKDM4E
SCHEMBL27482276 0.83 FABP7 (0.38) POLBMAPTKDM4EALDH1A1HPGD
SCHEMBL5468974 0.82 KDM4E (0.54) KMT2ALMNAMAPTKDM4EALDH1A1
SCHEMBL28133750 0.82 ALDH1A1 (0.51) GAAKMT2AMAPTKDM4EALDH1A1
SCHEMBL27475534 0.81 PPARG (0.44) GAAATMPOLBKMT2ALMNA
SCHEMBL27182663 0.79 PRSS1 (0.44) GAAATMKMT2ALMNAMAPT
SCHEMBL14520142 0.79 L3MBTL1 (0.42) KMT2ALMNASMN1; SMN2CA1CA9
SCHEMBL28813670 0.78 GAA (0.47) GAAATMPOLBKMT2AJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191108-A1 TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2024-06-13 US claimed
CN-103429528-A Preventing or reducing scale in wet-process phosphoric acid production CYTEC TECH CORP 2013-12-04 CN claimed
US-20240191108-A1 TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2024-06-13 US disclosed
CN-104204125-A Method and apparatus for adhesive bonding in aqueous media ZHAO BOXIN 2014-12-10 CN disclosed
CN-102015674-B Modulators of dopamine neurotransmission NSAB FILIAL AF NEUROSEARCH SWEDEN AB SVERIGE (DK) 2014-10-29 CN disclosed
CN-102123763-B Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use thereof XENOPORT, INC. (US) 2014-10-08 CN disclosed
CN-102574966-B Method for gluing film-like substrates HENKEL AG & CO KGAA 2014-07-02 CN disclosed
CN-103476746-A Novel modulators of cortical dopaminergic- and NMDA-receptor-mediated glutamatergic neurotransmission NEUROSEARCH AS 2013-12-25 CN disclosed
CN-103429528-A Preventing or reducing scale in wet-process phosphoric acid production CYTEC TECH CORP 2013-12-04 CN disclosed
CN-103421442-A Moisture-proof material NITTO DENKO CORP 2013-12-04 CN disclosed
CN-102036976-B Modulators of dopamine neurotransmission NSAB AF NEUROSEARCH SWEDEN AB 2013-05-01 CN disclosed
CN-101076517-A Novel substituted piperidines as modulators of dopamine neurotransmission CARLSSON A RESEARCH AB (SE) 2007-11-21 CN disclosed
CN-1997630-A New disubstituted phenylpiperidines as modulators of dopamine neurotransmission NEUROSEARCH SWEDEN AB (SE) 2007-07-11 CN disclosed
CN-1997631-A New disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission NEUROSEARCH SWEDEN AB (SE) 2007-07-11 CN disclosed
CN-1319957-C Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin SHISEIDO CO LTD (JP) 2007-06-06 CN disclosed
CN-1249059-C novel piperidine carboxylic acid amide derivatives, process for their preparation and pharmaceutical compositions containing them SANOFI SYNTHELABO (FR) 2006-04-05 CN disclosed
CN-1549809-A Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin ������������ʽ���� 2004-11-24 CN disclosed
CN-1518549-A Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same ʥŵ��-�ϳ�ʵ���ҹ�˾ 2004-08-04 CN disclosed
CN-1076690-A SULFONAMIDOCARBOXAMIDES HOFFMANN LA ROCHE (CH) 1993-09-29 CN disclosed
CN-1067257-A Chemiluminescence method and composition LUMIGEN INC (US) 1992-12-23 CN disclosed