Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 13/20 | 0.75 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | DCAF15 | Q66K64 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588994 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL27982227 | 0.83 | SYK (0.71) | SYK | |
| SCHEMBL27969513 | 0.77 | SYK (0.68) | SYKPOLBRAD52RXFP1 | |
| SCHEMBL20162364 | 0.76 | SYK (0.79) | SYK | |
| SCHEMBL27981775 | 0.75 | SYK (0.52) | SYKTLR8TLR7 | |
| SCHEMBL27981781 | 0.74 | SYK (0.51) | SYKTLR8TLR7APPDCAF15 | |
| SCHEMBL27982207 | 0.73 | SYK (0.52) | SYKPOLBTLR8TLR7 | |
| SCHEMBL373863 | 0.72 | SYK (0.69) | SYK | |
| SCHEMBL588879 | 0.71 | SYK (1.00) | SYK | |
| SCHEMBL27981779 | 0.70 | SYK (0.55) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104069112-A | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INT | 2014-10-01 | — | — | CN | disclosed |