Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881402 | 0.89 | PPARA (0.49) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL6341293 | 0.88 | ACHE (0.46) | MEN1KMT2AHTTL3MBTL1KCNH2 | |
| SCHEMBL6349731 | 0.84 | ALOX5 (0.51) | ALDH1A1 | |
| SCHEMBL2574637 | 0.81 | MEN1 (0.44) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL6288278 | 0.81 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1LMNATHRA | |
| SCHEMBL1935310 | 0.79 | MEN1 (0.47) | PPARAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL360638 | 0.77 | GPR84 (0.34) | MEN1KMT2AHTTL3MBTL1CYP4A11 | |
| SCHEMBL15263236 | 0.76 | FFAR1 (0.38) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL11060568 | 0.76 | FFAR1 (0.38) | MEN1KMT2AHTTL3MBTL1ALDH1A1 | |
| SCHEMBL1027884 | 0.76 | MEN1 (0.47) | MEN1KMT2AHTTL3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | PPARA 1244/4885MEN1 375/4885KMT2A 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.