Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861683 | 0.87 | KMT2A (0.50) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL15710904 | 0.87 | ALDH1A1 (0.44) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL13468097 | 0.86 | ALDH1A1 (0.43) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL13280139 | 0.83 | KMT2A (0.43) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL5859715 | 0.80 | KDM4E (0.57) | KMT2AKDM4EHSD17B10POLB | |
| SCHEMBL27588091 | 0.79 | HPGD (0.67) | KMT2AALDH1A1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL31535354 | 0.78 | OPRK1 (0.44) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL27587960 | 0.78 | HPGD (0.65) | KMT2AALDH1A1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL25223224 | 0.77 | KMT2A (0.63) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL4444645 | 0.77 | KMT2A (0.67) | KMT2AALDH1A1KDM4EHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066718-A | Substituted benzene compounds | EPIZYME INC | 2014-09-24 | — | — | CN | disclosed |