Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 19/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980443 | 0.87 | FGFR2 (0.46) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL28825829 | 0.78 | DYRK3 (0.39) | — | |
| SCHEMBL27382297 | 0.76 | SRC (0.53) | — | |
| SCHEMBL27381319 | 0.74 | SRC (0.53) | — | |
| SCHEMBL15345690 | 0.73 | FGFR2 (0.69) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345611 | 0.72 | FGFR2 (0.76) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345610 | 0.72 | FGFR2 (0.76) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL20808463 | 0.71 | FGFR2 (0.55) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345562 | 0.69 | FGFR2 (0.59) | FGFR2FGFR1FGFR4FGFR3 | |
| SCHEMBL15345775 | 0.68 | FGFR2 (0.58) | FGFR2FGFR1FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958512-B | The two substituted alkynyl benzene compound of 3,5-and salt thereof | TAIHO PHARMACEUTICAL CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-103958512-A | 3,5-disubstituted alkynylbenzene compound and salt thereof | TAIHO PHARMACEUTICAL CO LTD | 2014-07-30 | — | — | CN | disclosed |