Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430546 | 0.76 | — | — | |
| Water SCHEMBL27505018 | 0.74 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL3335934 | 0.72 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL28452900 | 0.69 | — | — | |
| SCHEMBL1699822 | 0.68 | CA1 (0.30) | — | |
| Bromide SCHEMBL30530193 | 0.67 | MAPT (0.36) | ALDH1A1 | |
| Bromide SCHEMBL27407429 | 0.66 | — | — | |
| SCHEMBL8924718 | 0.64 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL571158 | 0.64 | — | — | |
| SCHEMBL3720585 | 0.64 | DNM1 (0.33) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104120603-A | Fabric antistatic agent and fabric antistatic finishing technology | UNIV GUANGZHOU | 2014-10-29 | — | — | CN | disclosed |