Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814636 | 1.00 | SLC6A3 (0.35) | SLC6A3ACHEKMT2ASLC6A4SLC6A2 | |
| SCHEMBL27874938 | 0.92 | SLC6A3 (0.39) | SLC6A3KMT2ASLC6A4SLC6A2KCNH2 | |
| SCHEMBL27727636 | 0.80 | ARG1 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL27836290 | 0.80 | KCNH2 (0.33) | KCNH2CACNA1I | |
| SCHEMBL31679477 | 0.80 | KMT2A (0.34) | KMT2A | |
| SCHEMBL27986606 | 0.79 | DPP8 (0.39) | KMT2A | |
| SCHEMBL27986607 | 0.79 | DPP8 (0.39) | KMT2A | |
| SCHEMBL27539771 | 0.77 | SMN1; SMN2 (0.49) | KMT2A | |
| SCHEMBL27552123 | 0.76 | HRH3 (0.40) | KCNH2 | |
| SCHEMBL27854244 | 0.75 | SMN1; SMN2 (0.36) | KMT2AKCNH2CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762101-B | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS LLC | 2014-09-17 | — | — | CN | disclosed |