Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477740 | 0.86 | S1PR1 (0.43) | TERTS1PR1S1PR3S1PR5LTA4H | |
| SCHEMBL29361958 | 0.85 | LTA4H (0.39) | S1PR1S1PR3S1PR5LTA4HHSD17B10 | |
| SCHEMBL10867079 | 0.84 | SPHK2 (0.45) | SPHK2SPHK1TERTS1PR1S1PR3 | |
| SCHEMBL2961968 | 0.82 | SPHK2 (0.45) | SPHK2SPHK1TERTHRH3POLB | |
| SCHEMBL2961964 | 0.82 | SPHK2 (0.45) | SPHK2SPHK1TERTHRH3POLB | |
| SCHEMBL23777202 | 0.81 | SPHK2 (0.56) | SPHK2SPHK1S1PR1S1PR3S1PR5 | |
| SCHEMBL7367083 | 0.81 | SPHK2 (0.56) | SPHK2SPHK1S1PR1S1PR3S1PR5 | |
| SCHEMBL3426506 | 0.80 | SPHK2 (0.43) | SPHK2SPHK1TERTS1PR1S1PR3 | |
| SCHEMBL23865736 | 0.80 | SPHK2 (0.58) | SPHK2SPHK1S1PR1S1PR3S1PR5 | |
| SCHEMBL23866033 | 0.80 | SPHK2 (0.58) | SPHK2SPHK1S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102342-B | Aminoquinazoline derivative, salts thereof and application method | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2014-10-29 | — | — | CN | disclosed |