Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.43 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424382 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL3431907 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL3430851 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL28814693 | 0.86 | SPHK2 (0.42) | S1PR1S1PR3S1PR5TERTLTA4H | |
| SCHEMBL3429337 | 0.83 | TERT (0.46) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL3429412 | 0.83 | TERT (0.46) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL3429301 | 0.83 | TERT (0.46) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL3431905 | 0.83 | S1PR1 (0.47) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL7165442 | 0.83 | S1PR1 (0.43) | S1PR1S1PR3S1PR5TERTS1PR4 | |
| SCHEMBL3424378 | 0.83 | S1PR1 (0.47) | S1PR1S1PR3S1PR5TERTS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |