Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590790 | 0.83 | ALDH1A1 (0.68) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL3150403 | 0.82 | ALDH1A1 (0.67) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL23247805 | 0.79 | ALDH1A1 (0.63) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL22102532 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL27918947 | 0.79 | PDGFRB (0.58) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL4337980 | 0.79 | ALDH1A1 (0.55) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL22815757 | 0.79 | CA12 (0.54) | ALDH1A1GLAF2HPGDCA2 | |
| SCHEMBL7594210 | 0.78 | ALDH1A1 (0.62) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL535665 | 0.77 | EGFR (0.64) | ALDH1A1GLAF2HPGDPDE3B | |
| SCHEMBL29869661 | 0.76 | MAP4K4 (0.46) | ALDH1A1GLAF2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104109166-A | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | SHANGHAI PHARMACEUTICALS HOLDING CO LTD | 2014-10-22 | — | — | CN | disclosed |