Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LGMN | Q99538 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093746 | 0.89 | LMNA (0.71) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2175616 | 0.82 | LMNA (0.62) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3948094 | 0.82 | LMNA (0.95) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2555823 | 0.82 | LMNA (0.95) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL254812 | 0.82 | LMNA (0.95) | LMNAMAPTALDH1A1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL4262260 | 0.80 | LMNA (0.91) | LMNAMAPTALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9131024 | 0.80 | LMNA (0.91) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL184087 | 0.80 | LMNA (0.91) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9092806 | 0.80 | LMNA (0.60) | LMNAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL13809379 | 0.80 | LMNA (1.00) | LMNAMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104185420-A | Antiviral JAK inhibitors for the treatment or prevention of retroviral and other viral infections | UNIV EMORY | 2014-12-03 | — | — | CN | claimed |