Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 7/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.31 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388020 | 0.78 | RAB9A (0.40) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL23165945 | 0.78 | NOTUM (0.36) | — | |
| SCHEMBL23166170 | 0.77 | NPC1 (0.33) | RAB9AMAPTHTTNPC1 | |
| SCHEMBL23167056 | 0.76 | PRMT5 (0.32) | — | |
| SCHEMBL23165672 | 0.75 | KMT2A (0.38) | MAPTHTTATMSMN1; SMN2L3MBTL1 | |
| SCHEMBL1770222 | 0.74 | HTT (0.51) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL23165965 | 0.74 | SCN9A (0.45) | KMT2A | |
| SCHEMBL23165702 | 0.74 | KDM4E (0.43) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL23166193 | 0.74 | BAZ2B (0.36) | KDM4EL3MBTL1KAT6AMEN1KMT2A | |
| SCHEMBL122970 | 0.72 | KEAP1 (0.53) | RAB9AMAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761000-A | Substituted 1, 6-naphthyridine inhibitors of CDK5 | 金翅雀生物公司 | 2022-07-15 | — | — | CN | claimed |