Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATF4 | P18848 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128560 | 0.69 | ERCC5 (0.41) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8875853 | 0.68 | GAA (0.48) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29943543 | 0.67 | GAA (0.47) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28816302 | 0.67 | GAA (0.47) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4714980 | 0.65 | TDP1 (0.42) | HPGDGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29037470 | 0.65 | HPGD (0.45) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28076474 | 0.64 | TSHR (0.47) | HPGDSMN1; SMN2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3930975 | 0.64 | PIK3CA (0.40) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29445578 | 0.64 | HPGD (0.47) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9562462 | 0.64 | GAA (0.42) | HPGDGAASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933543-B | Synthetic method of 3-cyclopropylamino-2- (2,4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-114933543-A | Synthetic method of 3-cyclopropylamino-2- (2, 4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-114933543-B | Synthetic method of 3-cyclopropylamino-2- (2,4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-114933543-A | Synthetic method of 3-cyclopropylamino-2- (2, 4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-08-23 | — | — | CN | disclosed |