Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241168 | 0.92 | GAA (0.49) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30680417 | 0.91 | ALDH1A1 (0.42) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30181504 | 0.88 | MEN1 (0.42) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29007819 | 0.88 | MEN1 (0.42) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7009795 | 0.87 | TDP1 (0.41) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6217850 | 0.86 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8875853 | 0.86 | GAA (0.48) | MEN1KMT2AGAACYP1A2CYP2C19 | |
| SCHEMBL29943543 | 0.84 | GAA (0.47) | MEN1KMT2AGAACYP1A2CYP2C19 | |
| SCHEMBL28816302 | 0.84 | GAA (0.47) | MEN1KMT2AALDH1A1GAACYP1A2 | |
| SCHEMBL8183324 | 0.84 | MEN1 (0.44) | TDP1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077429-A | 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-QUINOLINE- AND NAPHTHYRIDINE-3-CARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THESE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | claimed |
| CN-119264049-A | Norfloxacin Star synthesizing method | 中南大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-116693375-B | Synthesis method of 2, 4-dichloro-5-fluoro acetophenone | 山东国邦药业有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116693375-A | Synthesis method of 2, 4-dichloro-5-fluoro acetophenone | 山东国邦药业有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116462631-A | Synthetic method of norfloxacin | 青海夏都医药有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-115650831-B | Synthetic method of 2, 4-dichloro-5-fluoro acetophenone | 山东国邦药业有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115650831-A | Synthetic method of 2, 4-dichloro-5-fluoro acetophenone | 山东国邦药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-109422726-B | Blocking agent of CD47/SIRP alpha and application thereof | 华东理工大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-108440291-B | Method for dehydrogenation and self-coupling of 1, 3-dicarbonyl compound under catalysis of visible light | 南京工业大学 | 2020-08-28 | — | — | CN | disclosed |
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | VYMED CORPORATION (US) | 2014-03-13 | — | — | US | disclosed |
| EP-0230053-A2 | 7-(Substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4670444-A | 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyridine-3-carboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| US-4620007-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |
| US-4611080-A | Preparation of halogenated aroylacetic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| US-4563448-A | PHYTOPATHOGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4563459-A | FUNGICIDES AND BACTERICIDES FOR AGRICULTURAL USE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| US-4559341-A | Quinolonecarboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| US-4559342-A | Quinolone acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| US-4547503-A | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(oxo-alkyl)-1-piperazinyl]quinoline-3-carboxylic acids and their derivatives, and antibacterial agents containing them | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-15 | — | — | US | disclosed |
| US-4544658-A | FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073631-A1 | ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS | GDA, GMPS, GANC | TDP1 337/4885MEN1 4700/4885KMT2A 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.