Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29943543 | 0.98 | GAA (0.47) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL28816302 | 0.98 | GAA (0.47) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL9186659 | 0.92 | GAA (0.56) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL4714980 | 0.86 | TDP1 (0.42) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL10778540 | 0.86 | NPC1 (0.43) | GAALMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL9128560 | 0.81 | ERCC5 (0.41) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL28076474 | 0.79 | TSHR (0.47) | LMNAPOLBAPEX1MAPTSMN1; SMN2 | |
| SCHEMBL9248547 | 0.79 | ALPL (0.50) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL8876484 | 0.79 | GAA (0.42) | GAALMNAPOLBAPEX1MAPT | |
| SCHEMBL8877353 | 0.79 | GAA (0.41) | GAALMNAPOLBAPEX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105792-B | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114105792-A | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114105792-B | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114105792-B | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114920660-B | Synthesis method of cyclopropanecarboxylic acid intermediate | 山东国邦药业有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114920660-A | Method for synthesizing cyclopropanecarboxylic acid intermediate | 山东国邦药业有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114105792-A | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105792-A | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-107151242-B | 2-azolothiochromone compound, synthesis method thereof and application thereof in preparation of antifungal drugs | 南京工业大学 | 2020-05-22 | — | — | CN | disclosed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | disclosed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | disclosed |
| US-5672708-A | Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| US-4611080-A | Preparation of halogenated aroylacetic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | TXN2, TXN, TXNRD2 | GAA 4281/4885LMNA 3765/4885POLB 4077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.