Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557184 | 0.88 | MAPK1 (0.51) | MAPK1TSHRCYP2C19HPGDMAPT | |
| Ioglycamic Acid SCHEMBL29881458 | 0.88 | TSHR (0.70) | MAPK1TSHRKDM4CHPGDMAPT | |
| Ioglycamic Acid SCHEMBL433485 | 0.88 | TSHR (0.70) | MAPK1TSHRKDM4CHPGDMAPT | |
| SCHEMBL30129801 | 0.87 | TSHR (0.50) | MAPK1TSHRCYP2C19KDM4CHPGD | |
| Iotrizoic Acid SCHEMBL2111608 | 0.87 | TSHR (0.58) | MAPK1TSHRCYP2C19KDM4CHPGD | |
| Iotrizoic Acid SCHEMBL31409209 | 0.87 | TSHR (0.58) | MAPK1TSHRCYP2C19KDM4CHPGD | |
| Iotroxic Acid SCHEMBL38038 | 0.84 | TSHR (0.65) | MAPK1TSHRMAPTLMNASMN1; SMN2 | |
| Iotroxic Acid SCHEMBL27729545 | 0.84 | TSHR (0.65) | MAPK1TSHRMAPTLMNASMN1; SMN2 | |
| Iotetric Acid SCHEMBL27748028 | 0.84 | TSHR (0.65) | MAPK1TSHRMAPTLMNASMN1; SMN2 | |
| Iotetric Acid SCHEMBL37863 | 0.84 | TSHR (0.65) | MAPK1TSHRMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102964269-B | Novel preparation method of iopromide | ZHEJIANG HICHI PHARMACEUTICAL CO LTD | 2015-01-28 | — | — | CN | claimed |