Ioglycamic Acid

Ioglycamic Acid

SCHEMBL433485

O=C(COCC(=O)Nc1c(I)cc(I)c(C(=O)O)c1I)Nc1c(I)cc(I)c(C(=O)O)c1I

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
MAPK1 P28482 1/20 0.70
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 2/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
XBP1 P17861 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HIF1A Q16665 1/20 0.32
EPAS1 Q99814 1/20 0.32
TPMT P51580 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HPGD P15428 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ioglycamic Acid SCHEMBL29881458 1.00 TSHR (0.70) TSHRMAPK1KMT2AKDM4EMAPT
Iodipamide SCHEMBL10620456 0.93 TSHR (0.84) TSHRMAPK1KMT2AKDM4EMEN1
Iotroxic Acid SCHEMBL38038 0.93 TSHR (0.65) TSHRMAPK1KDM4EMAPTPOLB
Iotetric Acid SCHEMBL37863 0.93 TSHR (0.65) TSHRMAPK1KDM4EMAPTPOLB
SCHEMBL28816554 0.88 MAPK1 (0.67) TSHRMAPK1KMT2AMAPTGAA
Iotrizoic Acid SCHEMBL31409209 0.87 TSHR (0.58) TSHRMAPK1KDM4EMAPTPOLB
Iotrizoic Acid SCHEMBL2111608 0.87 TSHR (0.58) TSHRMAPK1KDM4EMAPTPOLB
Ioglycamic Acid SCHEMBL29726597 0.85 TSHR (0.51) TSHRMAPK1KMT2AMAPTMEN1
Iotranic Acid SCHEMBL2109613 0.84 TSHR (0.74) TSHRMAPK1KMT2AMEN1POLB
Iodoxamic Acid SCHEMBL377402 0.84 TSHR (0.74) TSHRMAPK1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170279-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
US-20250170280-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2025-05-29 US claimed
WO-2021238893-A1 EFFICIENT AND EFFECTIVE TISSUE CLEARING AGENTS AND THEIR COMPOSITIONS THE CHINESE UNIVERSITY OF HONG KONG (CN) 2021-12-02 WO claimed
US-20210145747-A1 CERASOME DELIVERY SYSTEM FOR TARGETING ACTIVATED CD44 MOLECULE, PREPARATION METHOD AND USE THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2021-05-20 US claimed
US-20200397926-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE,PREPARATION METHOD THEREFOR, AND USES THEREOF BEIJING INNO MEDICINE CO., LTD. (CN) 2020-12-24 US claimed
EP-3744317-A1 LIPOSOMAL NANOCARRIER DELIVERY SYSTEM FOR TARGETING ACTIVE CD44 MOLECULE, PREPARATION METHOD THEREFOR, AND USES THEREOF Beijing Inno Medicine Co., Ltd. (CN) 2020-12-02 EP claimed
EP-3610859-A1 CERASOME DELIVERY SYSTEM FOR USE IN TARGETED ACTIVATION OF CD44 MOLECULE, PREPARATION METHOD THEREFOR AND USE Beijing Inno Medicine Co., Ltd. (CN) 2020-02-19 EP claimed
CN-110402137-A A kind of silica nodule delivery system, preparation method and use for targeted activation CD44 molecule BEIJING INNO MEDICINE CO LTD 2019-11-01 CN claimed
EP-2706881-B1 RADIATION PROTECTION DEVICE AND METHODS THEREOF STEMRAD LTD (IL) 2018-07-25 EP claimed
CN-103841848-B Radioprotector and its method 施特姆拉德有限公司 2017-12-05 CN claimed
WO-1999004824-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, INC. (US) 1999-02-04 WO claimed
WO-1999001110-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 1999-01-14 WO claimed
CN-1189148-A 1, 3-propane diol derivatives as bioactive compounds SCOTIA HOLDINGS PLC (GB) 1998-07-29 CN claimed
CN-1187813-A Fatty acid esters as bioactive compounds SCOTIA HOLDINGS PLC (GB) 1998-07-15 CN claimed
US-5660814-A Iodinated paramagnetic chelates, and their use as contrast agents DIBRA S.P.A. (IT) 1997-08-26 US claimed
EP-0703790-A1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO S.p.A. (IT) 1996-04-03 EP claimed
WO-1994027644-A1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO S.P.A. (IT) 1994-12-08 WO claimed
EP-0274467-B1 HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM GEHO, W., Blair (US) 1992-05-20 EP claimed
EP-0050457-A1 Radiopaque cyanoacrylate compositions BioNexus, Inc. (US) 1982-04-28 EP claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210145747-A1 CERASOME DELIVERY SYSTEM FOR TARGETING ACTIVATED CD44 MOLECULE, PREPARATION METHOD AND USE THEREOF CD44, LDLR, PLAUR TSHR 3170/4885MAPK1 3939/4885KMT2A 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.