Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21839968 | 0.81 | NOTUM (0.56) | NOTUMKDM4ELMNACA12CA1 | |
| SCHEMBL184614 | 0.80 | NOTUM (0.67) | NOTUMKDM4ELMNACA12CA1 | |
| Methyl 3,5-Dibromobenzoate SCHEMBL2408987 | 0.80 | NOTUM (0.67) | NOTUMKDM4ELMNACA12CA1 | |
| Hydrochloric Acid SCHEMBL28532688 | 0.78 | NOTUM (0.53) | NOTUMKDM4ELMNACA12CA1 | |
| SCHEMBL21839899 | 0.78 | NOTUM (0.53) | NOTUMKDM4ELMNACA12CA1 | |
| SCHEMBL839253 | 0.77 | NOTUM (0.59) | NOTUMKDM4ELMNACA12CA1 | |
| SCHEMBL16397384 | 0.75 | GAA (0.55) | NOTUMKDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL2445250 | 0.75 | RAB9A (0.59) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL20839915 | 0.74 | ALDH1A1 (0.61) | NOTUMKDM4ELMNACA12CA1 | |
| SCHEMBL20839916 | 0.74 | KDM4E (0.49) | NOTUMKDM4ELMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402996-B | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD) | NOVARTIS AG | 2015-02-11 | — | — | CN | disclosed |