Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790316 | 0.83 | NFE2L2 (0.82) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL127539 | 0.83 | NFE2L2 (0.55) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL5963737 | 0.82 | NFE2L2 (0.62) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL5496405 | 0.82 | NFE2L2 (0.73) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL3904046 | 0.82 | NFE2L2 (0.73) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL1046285 | 0.80 | NFE2L2 (0.61) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL3998676 | 0.80 | NFE2L2 (0.61) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL1046286 | 0.80 | NFE2L2 (0.61) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL11437739 | 0.80 | NFE2L2 (0.66) | NFE2L2FBP1P4HBMEN1LMNA | |
| SCHEMBL2787109 | 0.80 | NFE2L2 (0.66) | NFE2L2FBP1P4HBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507910-A | Partially saturated nitrogen-containing heterocyclic compound | TAISHO PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | disclosed |