Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765508 | 0.93 | CNR1 (0.39) | FFAR1MAPTPPARD | |
| Sulfuric Acid SCHEMBL28914612 | 0.85 | CNR1 (0.42) | FFAR1MAPTPPARD | |
| SCHEMBL29015846 | 0.84 | LMNA (0.40) | CA2GGPS1 | |
| SCHEMBL28521713 | 0.82 | EPHX2 (0.38) | GRIK1GRIK2FFAR1MAPTPPARD | |
| SCHEMBL28339296 | 0.81 | CES2 (0.36) | GGPS1 | |
| SCHEMBL28504651 | 0.79 | MAPT (0.44) | MAPK1MAPT | |
| SCHEMBL28395366 | 0.79 | MAPT (0.44) | MAPK1MAPT | |
| SCHEMBL28334151 | 0.78 | CES2 (0.37) | GGPS1 | |
| SCHEMBL5940755 | 0.78 | CES2 (0.37) | GGPS1 | |
| SCHEMBL29281612 | 0.78 | CNR1 (0.40) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104508199-A | Method for restoring or increasing water absorption of polyester fabric | RHODIA OPERATIONS | 2015-04-08 | — | — | CN | claimed |
| CN-105278097-A | Low optical power hysteresis liquid lenses | PARROT | 2016-01-27 | — | — | CN | disclosed |
| CN-104508199-A | Method for restoring or increasing water absorption of polyester fabric | RHODIA OPERATIONS | 2015-04-08 | — | — | CN | disclosed |