Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497518 | 0.84 | FFAR4 (0.40) | KDM1AMAOBMAOAFFAR4PTPRF | |
| SCHEMBL3497521 | 0.84 | FFAR4 (0.40) | KDM1AMAOBMAOAFFAR4PTPRF | |
| SCHEMBL25860487 | 0.75 | CYP2C9 (0.43) | KDM1AMAOBMAOAKCNH2RCOR1 | |
| SCHEMBL23368653 | 0.75 | CYP2C9 (0.43) | KDM1AMAOBMAOAKCNH2RCOR1 | |
| SCHEMBL25860508 | 0.75 | CYP2C9 (0.43) | KDM1AMAOBMAOAKCNH2RCOR1 | |
| SCHEMBL28817171 | 0.74 | HIF1A (0.40) | FFAR4 | |
| SCHEMBL28413632 | 0.73 | AKR1C3 (0.47) | AKR1C3AKR1C1RAB9AATM | |
| SCHEMBL24040028 | 0.73 | AKR1C3 (0.47) | AKR1C3AKR1C1RAB9AATM | |
| SCHEMBL24040040 | 0.73 | AKR1C3 (0.47) | AKR1C3AKR1C1RAB9AATM | |
| SCHEMBL12814000 | 0.72 | KDM1A (0.48) | KDM1AMAOBMAOAKCNH2RCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |