Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872230 | 0.86 | PKM (0.55) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL30926055 | 0.84 | PKM (0.47) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL27237644 | 0.84 | GAA (0.51) | SMN1; SMN2RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL11163786 | 0.84 | PKM (0.47) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL1116017 | 0.83 | KDM4E (0.45) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL15203544 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL1056662 | 0.81 | MEN1 (0.45) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| SCHEMBL9732800 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL34472491 | 0.81 | TDP1 (0.52) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27342283 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |