Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607816 | 1.00 | MEN1 (0.44) | MEN1KMT2ANPC1GAACYP2C19 | |
| SCHEMBL28817077 | 1.00 | MEN1 (0.44) | MEN1KMT2ANPC1GAACYP2C19 | |
| SCHEMBL4607546 | 0.87 | SCN1A (0.44) | DDB1CRBNALDH1A1CHRM2OPRM1 | |
| SCHEMBL4607545 | 0.87 | SCN1A (0.44) | DDB1CRBNALDH1A1CHRM2OPRM1 | |
| SCHEMBL4607495 | 0.86 | MEN1 (0.45) | MEN1KMT2AGAAGRIA4ALDH1A1 | |
| SCHEMBL4607494 | 0.86 | MEN1 (0.45) | MEN1KMT2AGAAGRIA4ALDH1A1 | |
| SCHEMBL25341814 | 0.85 | RAB9A (0.44) | MEN1KMT2AGAACYP2C9GRIA4 | |
| SCHEMBL12860003 | 0.84 | SMO (0.46) | MEN1KMT2ANPC1GAACYP2C19 | |
| SCHEMBL31330266 | 0.84 | KDM1A (0.43) | MEN1KMT2ADDB1CRBNALDH1A1 | |
| SCHEMBL13949557 | 0.72 | DDB1 (0.39) | MEN1KMT2AGAADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |