Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PTPRB | P23467 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031311 | 0.89 | HPGD (0.62) | HPGDHSD17B10PTPRBCYP3A4USP2 | |
| SCHEMBL21807185 | 0.89 | USP2 (0.46) | HSD17B10MAPTNPC1RAB9AUSP2 | |
| SCHEMBL25648755 | 0.81 | HPGD (0.50) | HPGDHSD17B10PTPRBMAPTNPC1 | |
| SCHEMBL23885544 | 0.81 | CYP1A2 (0.43) | HPGDMAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL31218457 | 0.80 | ALDH1A1 (0.45) | HPGDHSD17B10PTPRBMAPTMEN1 | |
| SCHEMBL21979989 | 0.80 | ALDH1A1 (0.45) | HPGDHSD17B10PTPRBMAPTMEN1 | |
| SCHEMBL31748002 | 0.77 | KDM4E (0.44) | HPGDHSD17B10PTPRBMAPTNPC1 | |
| SCHEMBL25272394 | 0.76 | ALDH1A1 (0.46) | HPGDHSD17B10PTPRBMAPTNPC1 | |
| SCHEMBL6433021 | 0.76 | ALDH1A1 (0.57) | HPGDHSD17B10PTPRBMAPTNPC1 | |
| SCHEMBL31465663 | 0.75 | ALDH1A1 (0.47) | HPGDHSD17B10PTPRBMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |