Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218457 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AHPGDPTPRB | |
| SCHEMBL1601877 | 0.90 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AHPGDPTPRB | |
| SCHEMBL6354671 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTKCNJ11 | |
| SCHEMBL28383668 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AHPGDTAS1R3 | |
| SCHEMBL28817153 | 0.80 | HPGD (0.51) | ALDH1A1MEN1KMT2AHPGDPTPRB | |
| SCHEMBL25096707 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL30254447 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL23885497 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11619402 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHPGDPTPRB | |
| SCHEMBL8528629 | 0.78 | AKR1C3 (0.52) | ALDH1A1MEN1KMT2AHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12384789-B2 | Compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| EP-3634953-B1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-01-03 | — | — | EP | disclosed |
| EP-4151627-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2023-03-22 | — | — | EP | disclosed |
| US-20220251098-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. | 2022-08-11 | — | — | US | disclosed |
| US-11407753-B2 | Compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200165256-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. | 2020-05-28 | — | — | US | disclosed |
| CN-111065626-A | Compounds for the treatment of huntington's chorea | PTC医疗公司 | 2020-04-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251098-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, FH | ALDH1A1 1524/4885MEN1 1629/4885KMT2A 1146/4885 |
| US-20200165256-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, FH | ALDH1A1 1524/4885MEN1 1629/4885KMT2A 1146/4885 |
| US-11407753-B2 | Compounds for treating Huntington's disease | HTT, HYPK, FH | ALDH1A1 1524/4885MEN1 1629/4885KMT2A 1146/4885 |
| US-12384789-B2 | Compounds for treating Huntington's disease | HTT, HYPK, FH | ALDH1A1 1524/4885MEN1 1629/4885KMT2A 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.