Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817222 | 0.88 | RAB9A (0.32) | HPGDCYP3A4MAPTALDH1A1RAB9A | |
| SCHEMBL28817180 | 0.81 | ALDH1A1 (0.50) | HPGDCYP3A4MAPTALDH1A1GAA | |
| SCHEMBL17843992 | 0.79 | CDC7 (0.46) | HPGDCYP3A4MAPTALDH1A1GAA | |
| SCHEMBL29784790 | 0.74 | CDC7 (0.38) | HPGDCYP3A4MAPTALDH1A1GAA | |
| SCHEMBL17844000 | 0.72 | MAPT (0.44) | HPGDMAPTALDH1A1NPSR1RAB9A | |
| SCHEMBL28817179 | 0.72 | CDC7 (0.34) | HPGDCYP3A4MAPTALDH1A1GAA | |
| SCHEMBL1560797 | 0.71 | PTPN1 (0.47) | HPGDMAPTALDH1A1GAANPSR1 | |
| SCHEMBL17843999 | 0.68 | ALDH1A1 (0.43) | HPGDMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL9732800 | 0.68 | ALDH1A1 (0.50) | MAPTALDH1A1GAAMAPK1NPSR1 | |
| SCHEMBL29706009 | 0.67 | HSD17B10 (0.52) | HPGDMAPTALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341774-B | Substituted quinolinone inhibitors | 首药控股(北京)股份有限公司 | 2022-07-19 | — | — | CN | disclosed |