Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 9/20 | 0.43 |
| ▸ | CCNK | O75909 | 9/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.43 |
| ▸ | CDK2 | P24941 | 9/20 | 0.43 |
| ▸ | CDK9 | P50750 | 9/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 9/20 | 0.43 |
| ▸ | CDK7 | P50613 | 8/20 | 0.40 |
| ▸ | CCNH | P51946 | 8/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007128 | 1.00 | CCNT1 (0.43) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL30716225 | 0.84 | RPS6KA5 (0.38) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL26696831 | 0.84 | RPS6KA5 (0.38) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL30359906 | 0.80 | PIN1 (0.43) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL22076269 | 0.79 | CCNK (0.48) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL24588844 | 0.70 | DYRK1A (0.53) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL29699124 | 0.70 | DYRK1A (0.53) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL30716336 | 0.70 | CCNT1 (0.32) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL26697039 | 0.70 | CCNT1 (0.32) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL21179174 | 0.68 | CCNK (0.49) | CCNT1CCNKCCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907407-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 江苏先声药业有限公司 | 2022-08-16 | — | — | CN | disclosed |