Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933887 | 0.89 | — | — | |
| SCHEMBL21585592 | 0.85 | — | — | |
| SCHEMBL30327706 | 0.84 | NR1H2 (0.36) | — | |
| SCHEMBL1791330 | 0.84 | HSD17B10 (0.30) | — | |
| SCHEMBL1786234 | 0.84 | HSD17B10 (0.30) | — | |
| SCHEMBL344780 | 0.84 | HSD17B10 (0.30) | — | |
| SCHEMBL18393475 | 0.84 | HSD17B10 (0.30) | — | |
| SCHEMBL344781 | 0.84 | HSD17B10 (0.30) | — | |
| SCHEMBL2586890 | 0.81 | HSD17B10 (0.36) | — | |
| SCHEMBL18007258 | 0.81 | HSD17B10 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107532229-B | Process for leaching metal sulphides with an agent having a thiocarbonyl function | 不列颠哥伦比亚大学 | 2021-10-08 | — | — | CN | claimed |
| EP-3722298-B1 | PYRROLO(PYRAZOLO)PYRIMIDINE DERIVATIVE AS LRRK2 INHIBITOR | OSCOTEC INC (KR) | 2023-08-02 | — | — | EP | disclosed |
| CN-110352256-B | Process for leaching metal sulphides with an agent having a thiocarbonyl function | 捷迪资源有限责任公司 | 2023-01-10 | — | — | CN | disclosed |
| US-11370796-B2 | Substituted pyrazoles as LRRK2 inhibitors | OSCOTEC INC. (KR) | 2022-06-28 | — | — | US | disclosed |
| US-20210363144-A1 | PYRROLO(PYRAZOLO)PYRIMIDINE DERIVATIVE AS LRRK2 INHIBITOR | OSCOTEC INC. (KR) | 2021-11-25 | — | — | US | disclosed |
| EP-3722298-A1 | PYRROLO(PYRAZOLO)PYRIMIDINE DERIVATIVE AS LRRK2 INHIBITOR | Oscotec Inc. (KR) | 2020-10-14 | — | — | EP | disclosed |
| EP-2807162-B1 | SUBSTITUTED PHENYLIMIDAZOPYRAZOLES AND USE THEREOF | Bayer Pharma AG (DE) | 2017-06-07 | — | — | EP | disclosed |
| EP-2590969-B1 | Therapeutic agents 976 | ASTRAZENECA AB (SE) | 2014-10-15 | — | — | EP | disclosed |
| US-20100261699-A1 | N-PYRAZOLE-2-PYRIDINE CARBOXAMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| EP-2236507-A1 | N-PYRAZOLE-2-PYRIDINECARBOXAMIDE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363144-A1 | PYRROLO(PYRAZOLO)PYRIMIDINE DERIVATIVE AS LRRK2 INHIBITOR | LRRK2, PARK7, WEE1 | POLB 916/4885 |
| US-11370796-B2 | Substituted pyrazoles as LRRK2 inhibitors | LRRK2, PARK7, PAK3 | POLB 1894/4885 |
| US-20100261699-A1 | N-PYRAZOLE-2-PYRIDINE CARBOXAMIDE DERIVATIVE | GCKR, GPR119, GCK | POLB 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.