Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.68 |
| ▸ | PKM | P14618 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252134 | 0.97 | MAPT (0.72) | MAPTPKMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL28252821 | 0.85 | LMNA (0.67) | MAPTPKMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL28252139 | 0.83 | MAPT (0.68) | MAPTPKMPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8859451 | 0.80 | MAPT (0.66) | MAPTPKMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL1958584 | 0.78 | MAPT (0.75) | MAPTPKMPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28228303 | 0.78 | MAPT (0.64) | MAPTPKMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL2481610 | 0.78 | SMN1; SMN2 (0.93) | MAPTPKMPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28237244 | 0.77 | MAPT (0.62) | MAPTPKMPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1957440 | 0.77 | MAPT (0.77) | MAPTPKMPOLBSMN1; SMN2GAA | |
| SCHEMBL6954918 | 0.77 | MAPT (0.69) | MAPTPKMPOLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794358-B | Substituted benzenesulfonyl compounds and application thereof in preparing medicines | 中国人民解放军第二军医大学 | 2022-08-12 | — | — | CN | disclosed |