SCHEMBL28817475

SCHEMBL28817475

CCc1nc(C)cn1-n1cc(C)nc1CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
HTT P42858 4/20 0.41
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 5/20 0.39
MAPT P10636 2/20 0.39
CYP19A1 P11511 1/20 0.39
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 1/20 0.35
PDE2A O00408 1/20 0.35
PDE1A P54750 1/20 0.35
PDE1B Q01064 1/20 0.35
PDE3B Q13370 1/20 0.35
PDE1C Q14123 1/20 0.35
PDE3A Q14432 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
GPR55 Q9Y2T6 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27508793 0.80 TSHR (0.34) LMNAHTTTSHRSMN1; SMN2MAPT
SCHEMBL27779486 0.79 TSHR (0.33) LMNAHTTTSHRSMN1; SMN2MAPT
SCHEMBL2512278 0.78
SCHEMBL29157792 0.78 SMN1; SMN2 (0.33) LMNAHTTTSHRSMN1; SMN2MAPT
SCHEMBL27353368 0.76
SCHEMBL27846602 0.76
SCHEMBL27624956 0.76
SCHEMBL27306894 0.76
SCHEMBL6855316 0.76 CYP19A1 (0.47) LMNAHTTTSHRSMN1; SMN2MAPT
Ethane SCHEMBL28231212 0.75 LMNA (0.36) LMNAHTTTSHRSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104583309-A Resin composition, and copper coil substrate and printed circuit board thereof ELITE ELECTRONIC MATERIAL KUNSHAN CO LTD 2015-04-29 CN disclosed