Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26073020 | 0.92 | GPR84 (0.39) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3443498 | 0.92 | GPR84 (0.39) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL16639193 | 0.82 | GPR84 (0.47) | GPR84TDP1ALDH1A1 | |
| SCHEMBL5490601 | 0.81 | GPR84 (0.55) | GPR84TDP1ALDH1A1 | |
| SCHEMBL28288468 | 0.79 | GPR84 (0.58) | GPR84TDP1ALDH1A1 | |
| SCHEMBL7777918 | 0.78 | CACNA2D1 (0.36) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3015727 | 0.76 | TSHR (0.34) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4378802 | 0.76 | TSHR (0.34) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3015730 | 0.76 | TSHR (0.34) | GPR84CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4387847 | 0.76 | TSHR (0.34) | GPR84CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114908075-A | Method for synthesizing brivaracetam chiral intermediate by enzyme method | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |